What is a DVT (Deep Vein Thrombosis)?

A deep vein thrombosis is a blood clot that forms most commonly in the deep veins of the leg. Here is what causes one, how it presents, and why it matters.

Joseph M. Caruso, MD, FACSJoseph M. Caruso, MD, FACSFounder & Vascular Surgeon
January 31, 2021
Cross-section illustration of a deep leg vein with a blood clot lodged against the valve, blocking the channel

What is a DVT?

Deep vein thrombosis (DVT) is a blood clot that forms most commonly in the deep veins of the leg. Clinically significant DVTs are any clot in the popliteal vein (vein behind the knee) and higher up. Causes of DVT are trauma, prolonged stasis (immobility usually related to disease or injury) or a hypercoagulable (prone to forming clot) disorder. They are common after trauma especially with long bone fractures. Most commonly they will cause discomfort and acute leg swelling (in the involved leg only). They can also present with pulmonary embolus. With PE, the clot breaks off and migrates through the heart into the lungs blocking blood flow to certain portions of the lung. This can be a life threatening even fatal event depending on the size of the clot.

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